Searchable abstracts of presentations at key conferences in endocrinology

ea0012p98 | Reproduction | SFE2006

Polyunsaturated fatty acids in vivo and in vitro affect expression of steroidogenic acute regulatory protein in steroidogenic tissues

Hodges LM , Chin EC , Nadaffy JM , Brickell J , Cheng Z , Sheldrick EL , Flint APF , Wathes DC , Abayasekara DRE

Public health policy in recent years has favoured a reduction in saturated fats in favour of polyunsaturated fats due to the numerous health benefits of polyunsaturated fatty acids (PUFAs). Previous studies have demonstrated that PUFAs modulate gonadal steroidogenesis. We have therefore investigated the hypothesis that PUFAs modify steroidogenesis through affecting components of the cholesterol metabolising machinery, including steroidogenic acute regulatory (StAR) protein and...